Alexa Demie recalled three spooky coincidences before being cast in Euphoria. The first was that she remembered seeing Jacob Elordi at the first audition and instantly felt he'd play Nate. The second was when Alexa went to a sandwich shop and "Euphoria" was one of the cheese names. And the third was that Alexa had a dream about being friends with Zendaya before the two even met.
Maude Apatow was always meant to be on the show. Sam Levinson and Maude having previously worked together on Assassination Nation, he loved how she was "so natural, vulnerable, and quiet." He kept her in mind while writing the Euphoria script.
The trivia item below may give away important plot points.
The finale episode contains a scene in which Nate beats his head against the floor. Jacob Elordi said in a interview that following the shooting of this scene, he had a serious concussion. After hearing this, creator Sam Levinson said he was never aware of such a problem, and suggested Jacob Elordi might be lying, still being in the skin of Nate Jacobs.