A cunning new adversary's carefully crafted plans force Mac to make an impossible choice: save the life of a friend, or save hundreds of innocent lives; Mac receives new information that will drive a wedge between him ...
Using a screwdriver and bug spray, MacGyver must find the U.S. government mole who is leaking classified intel to the organization that is trying to take down The Phoenix Foundation. Also, Sarah returns to help with the mission, and Nikki reappears, but Mac can't tell which side she's on.
On the way back from capturing a war criminal, Mac and Jack's helicopter crashes in a remote area of Kazakhstan, injuring their pilot and allowing their prisoner to escape with Jack's gun. Using a large blade and a water bottle, MacGyver must get help as the pilot's condition worsens and before the war criminal takes them as prisoners.
While tracking down the dangerous fugitive Aaron Deckard, Mac and Jack face the notorious Colton family of bounty hunters who already kidnapped their mark. Now, using a hook and a car cable, Mac must extract the criminal from the Colton's, who are unaware of the deadly situation they're in. Also, Bozer and Riley try to hack into Jack's CIA file to find out about his history with Matty.
Bozer's first overseas mission goes terribly wrong when Mac and the team are blamed for a terrorist bombing and the Phoenix Foundation is forced to disavow them. Using a ruler and coconut oil to make disguises, the team must avoid authorities and clear their names without any support from back home.
Mac, Dalton, and Cage pursue terrorists who have obtained a canister of deadly nerve gas; Bozer has been paired with Leanna for interrogation resistance training; Riley considers accepting her estranged father's invitation to dinner.
Mac helps a group of researchers trapped in the Arctic Ocean on a research vessel; Jack kidnaps Elwood, only to end up helping him deal with his past; Bozer and Leanna find themselves handcuffed together in a new test.