Derek and Meredith try to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to Bailey, who warns Meredith to end the relationship. Meanwhile, George suspects an anesthesiologist of drinking on the job, Alex treats a former competitor who now finds honor in self-mutilation, Izzie has to deal with a patient who won't let his girlfriend go, literally, and Cristina battles a case of what seems to be the flu.
Did You Know?
The episode's title references the song "The Self-Destruct Button", originally sung by Dana Monteith. See more
When Dr. Shepherd is getting ready for the hemispherectomy, he drinks an espresso after scrubbing and does not re-scrub before surgery. No surgeon would handle food or drink after scrubbing. See more
Dr. Meredith Grey
You don't know this yet, but life isn't supposed to be like this. It's not supposed to be this hard.
Cosy in the Rocket
(Main Title Theme)
Written by Carim Clasmann
and Galia Durant
Performed by Psapp See more