Denny & Izzie

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1. Grey's Anatomy (2005– )
Episode: Begin the Begin (2006)

TV-14 | 60 min | Drama, Romance

Izzie becomes attracted to a male patient with a heart condition, and George treats Bex, an intersex patient. Meanwhile, Meredith's mother receives a visitor, and Derek and Addison's relationship is still rocky.

Director: Jessica Yu | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 914

2. Grey's Anatomy (2005– )
Episode: What Have I Done to Deserve This? (2006)

TV-14 | 60 min | Drama, Romance

Meredith and George face the consequences of their actions, Izzie gets closer to Denny, who has been readmitted, and Addison asks for Bailey's help with an embarrassing ailment.

Director: Wendey Stanzler | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 877

3. Grey's Anatomy (2005– )
Episode: Band-Aid Covers the Bullet Hole (2006)

TV-14 | 60 min | Drama, Romance

Cristina babysits for Bailey and does not take to it well at all. Meanwhile, Addison and Derek come to terms with their relationship, George connects with Callie, and Denny continues to come between Alex and Izzie.

Director: Julie Anne Robinson | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 847

4. Grey's Anatomy (2005– )
Episode: Superstition (2006)

TV-14 | 43 min | Drama, Romance

Superstition strikes, with the interns convinced a series of deaths will occur. A complication from the LVAD surgery puts Denny in the OR, Cristina plans to make George move out, and Richard's old AA sponsor is admitted for treatment.

Director: Tricia Brock | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 840

5. Grey's Anatomy (2005– )
Episode: The Name of the Game (2006)

TV-14 | 60 min | Drama, Romance

Cristina is desperate for George to move out of the apartment, while Izzie is jealous of Callie's relationship with him. Meanwhile, Cristina and Richard are rivals in a surgery seminar, and Meredith discovers a secret about her father.

Director: Seith Mann | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 855

6. Grey's Anatomy (2005– )
Episode: Blues for Sister Someone (2006)

TV-14 | 60 min | Drama, Romance

Meredith considers going on a date with Finn, and Izzie tries to find out more about George and Callie. Meanwhile, Alex clashes with Addison over a sensitive case, and Burke is nervous about operating on a patient who is one of his heroes.

Director: Jeff Melman | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 874

7. Grey's Anatomy (2005– )
Episode: Damage Case (2006)

TV-14 | 60 min | Drama, Romance

The victims of a serious car accident are admitted, with every surgeon required to help. Meanwhile, Callie's forwardness grates on Izzie, Addison makes Alex suffer, and Derek takes his frustration out on Meredith.

Director: Tony Goldwyn | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 918

8. Grey's Anatomy (2005– )
Episode: 17 Seconds (2006)

TV-14 | 60 min | Drama, Romance

The victims of a workplace shooting are admitted. Izzie puts her job on the line to ensure Denny gets a new heart, Callie makes an effort with Meredith, and Addison is suspicious of Derek.

Director: Daniel Minahan | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,207

9. Grey's Anatomy (2005– )
Episode: Deterioration of the Fight or Flight Response (2006)

TV-14 | 60 min | Drama, Romance

Burke is admitted as a patient, along with Richard's niece. Izzie and the others fight to keep Denny alive, while Alex tries to secure the donor heart for him.

Director: Rob Corn | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,242

10. Grey's Anatomy (2005– )
Episode: Losing My Religion (2006)

TV-14 | 41 min | Drama, Romance

Richard is determined to discover the guilty party, and punishes the interns by making them arrange a prom for his niece. Meanwhile, Callie presses George about his feelings, and Derek and Meredith have to make a decision about Doc.

Director: Mark Tinker | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,659

11. Grey's Anatomy (2005– )
Episode: Time Has Come Today (2006)

TV-14 | 60 min | Drama, Romance

Everyone reminisces about the past. Meanwhile, Izzie is emotionally devastated, with the others trying to help her, Adele gives Richard an ultimatum, and George and Derek are put in quarantine when an outbreak of the plague is suspected.

Director: Daniel Minahan | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,183

12. Grey's Anatomy (2005– )
Episode: What I Am (2006)

TV-14 | 60 min | Drama, Romance

Meredith becomes a patient, and Derek and Addison are equally angry at Richard for allowing Mark to join the staff. Meanwhile, Izzie receives a visit from Denny's father, and Burke is plagued by doubt over his ability to return to surgery.

Director: Dan Lerner | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 907

13. Grey's Anatomy (2005– )
Episode: Six Days: Part 1 (2007)

TV-14 | 60 min | Drama, Romance

As George's father's surgery approaches, he begins to realize how serious his condition is. Meanwhile, Izzie has to prove to Bailey that she is ready to scrub in on a surgery, and Meredith keeps running into her father.

Director: Greg Yaitanes | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,012

14. Grey's Anatomy (2005– )
Episode: Six Days: Part 2 (2007)

TV-14 | 60 min | Drama, Romance

George's father's surgery has left him very weak, Izzie's act of generosity backfires on her, Cristina and Burke continue their war of silence, and Meredith reaches out to her father.

Director: Greg Yaitanes | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,041

15. Grey's Anatomy (2005– )
Episode: Great Expectations (2007)

TV-14 | 60 min | Drama, Romance

George deals with his grief, Cristina and Burke continue to ignore each other, Addison avoids Alex, and Izzie decides to help Bailey with a project. Meanwhile, Richard makes a decision which sends all the attendings scrambling.

Director: Michael Grossman | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 835

16. Grey's Anatomy (2005– )
Episode: Wishin' and Hopin' (2007)

TV-14 | 60 min | Drama, Romance

A toxic patient wreaks havoc. Meanwhile, Bailey opens the free clinic, but the lack of patients makes Izzie question her investment. Meredith's mother is admitted again, and Cristina makes Burke wait for an answer.

Director: Julie Anne Robinson | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 854

17. Grey's Anatomy (2005– )
Episode: Walk on Water (2007)

TV-14 | 60 min | Drama, Romance

The interns each react differently to a mass-casualty incident. Meanwhile, George crosses the professional line with Callie, Cristina asks Burke to keep quiet about their engagement, and Richard dons a new hairstyle.

Director: Rob Corn | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,035

18. Grey's Anatomy (2005– )
Episode: Drowning on Dry Land (2007)

TV-14 | 60 min | Drama, Romance

Izzie fights to save her patient's life, George searches for the son of his patient, and Alex has to contend with the relatives of victims. Meanwhile, Meredith is unconscious underwater, with Derek her only hope.

Director: Rob Corn | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,173

19. Grey's Anatomy (2005– )
Episode: Some Kind of Miracle (2007)

TV-14 | 60 min | Drama, Romance

An unconscious Meredith interacts with some ghosts from her past while Richard, Burke and Bailey devise an unusual method of reviving her. A despondent Cristina leaves during her shift, and Derek speaks his mind to Meredith's mother.

Director: Adam Arkin | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,196

20. Grey's Anatomy (2005– )
Episode: Dream a Little Dream of Me: Part 1 (2008)

TV-14 | 60 min | Drama, Romance

Meredith and Derek find that "happily ever after" isn't as easy as they hoped, Cristina finds interest in a military doctor, and the Chief is surprised to hear that Seattle Grace is no longer ranked as a top-tier teaching hospital.

Directors: Rob Corn, Michael Pressman | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 935

21. Grey's Anatomy (2005– )
Episode: Dream a Little Dream of Me: Part 2 (2008)

TV-14 | 60 min | Drama, Romance

As a group of best friends deal with the aftermath of their car crash, Dr. Torres takes the lead on a groundbreaking course of treatment for one of the patients. Meanwhile, Major Hunt ... See full summary »

Directors: Rob Corn, Michael Pressman | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 618

22. Grey's Anatomy (2005– )
Episode: Rise Up (2008)

TV-14 | 41 min | Drama, Romance

The residents and interns squabbling over procedures upsets Dr. Hunt, Erica discovers what happened to the heart she lost, and Derek asks Sloan to break out the McSteamy to distract Yang.

Director: Joanna Kerns | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 935

23. Grey's Anatomy (2005– )
Episode: These Ties That Bind (2008)

TV-14 | 43 min | Drama, Romance

Izzie wrestles with her ghost, Torres uses a ground-breaking procedure to get her mind off of Hahn, and the interns continue teaching themselves spurred on by a new cohort.

Director: Eric Stoltz | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 983

24. Grey's Anatomy (2005– )
Episode: In the Midnight Hour (2008)

TV-14 | 60 min | Drama, Romance

Sadie manipulates the interns into performing a procedure that goes horribly wrong, Izzie's ghost refuses to leave, and Mark bonds with a girl who's taken responsibility for her sleep-walking father.

Director: Tom Verica | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 976

25. Grey's Anatomy (2005– )
Episode: All by Myself (2008)

TV-14 | 60 min | Drama, Romance

The residents make their cases for the solo surgery, Sadie chafes at her restrictions, and Sloan battles his desires.

Director: Arlene Sanford | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 955

26. Grey's Anatomy (2005– )
Episode: Wish You Were Here (2009)

TV-14 | 60 min | Drama, Romance

Derek has trouble with objectivity concerning his death row patient, Cristina and Meredith continue their feud, Izzie confides her problem to Alex, and the Chief faces what's become of his life's work.

Director: Rob Corn | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 744

27. Grey's Anatomy (2005– )
Episode: Sympathy for the Devil (2009)

TV-14 | 60 min | Drama, Romance

Derek's mother visits, the death row patient starts angling for death in the hospital, Izzie craves more in her relationships, and Jackson's need for organs becomes critical.

Director: Jeannot Szwarc | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,031

28. Grey's Anatomy (2005– )
Episode: Stairway to Heaven (2009)

TV-14 | 60 min | Drama, Romance

Meredith and Miranda each cross a line, William Dunn regrets his decision and Izzie finally confronts what Denny's appearance means.

Director: Allison Liddi-Brown | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,206

29. Grey's Anatomy (2005– )
Episode: What a Difference a Day Makes (2009)

TV-14 | 60 min | Drama, Romance

A car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if the oversight is ... See full summary »

Director: Rob Corn | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,290

30. Grey's Anatomy (2005– )
Episode: Here's to Future Days (2009)

TV-14 | 55 min | Drama, Romance

Izzie is torn over whether to have Derek's proposed brain surgery. A soldier on medical leave asks for a radical operation so he can return to active duty. The Chief tries to lure Bailey ... See full summary »

Director: Bill D'Elia | Stars: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers

Votes: 1,077



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